Biological process  Transport  Molecular function  Transporter activity   Protein   ATP-binding cassette, sub-family A (ABC1), member 2  Gene symbol   ABCA2    Cellular component           Component Cytoplasm Lysosome         Experimental evidence      Total number of studies : 3       Peptide sequence Method Platform  Sample  Reference Mass spectrometry Plasma Liu et al. 2007 Mass spectrometry IMS-TOF Plasma Valentine et al. 2006 Mass spectrometry LTQ FT Serum Sennels et al. 2007          Multiple reaction monitoring data           Peptide sequence MH+ Sample Number of studies Reference Data not present           Protein concentration             Protein concentration Method Sample Reference Data not present           Extracellular vesicle proteins             Sample Isolation  Experimental method Vesiclepedia accession Reference Data not present          Architecture           Domains Motifs AAA   2069 - 2252 AAA   1007 - 1193 TM   1988 - 2010 TM   1946 - 1978 TM   1905 - 1927 TM   1876 - 1898 TM   1845 - 1867 TM   1794 - 1815 TM   892 - 914 TM   813 - 835 TM   784 - 806 TM   750 - 772 TM   707 - 729 TM   22 - 40          External links           HPRD UniProt NetPath  08967  Q9HC28,Q9BZC7  NetPath_M20             Protein sequence  NP_001597.2               MGFLHQLQLL LWKNVTLKRR SPWVLAFEIF IPLVLFFILL GLRQKKPTIS VKEVSFYTAA PLTSAGILPV MQSLCPDGQR DEFGFLQYAN STVTQLLERL DRVVEEGNLF DPARPSLGSE LEALRQHLEA LSAGPGTSGS HLDRSTVSSF SLDSVARNPQ ELWRFLTQNL SLPNSTAQAL LAARVDPPEV YHLLFGPSSA LDSQSGLHKG QEPWSRLGGN PLFRMEELLL APALLEQLTC TPGSGELGRI LTVPESQKGA LQGYRDAVCS GQAAARARRF SGLSAELRNQ LDVAKVSQQL GLDAPNGSDS SPQAPPPRRL QALLGDLLDA QKVLQDVDVL SALALLLPQG ACTGRTPGPP ASGAGGAANG TGAGAVMGPN ATAEEGAPSA AALATPDTLQ GQCSAFVQLW AGLQPILCGN NRTIEPEALR RGNMSSLGFT SKEQRNLGLL VHLMTSNPKI LYAPAGSEVD RVILKANETF AFVGNVTHYA QVWLNISAEI RSFLEQGRLQ QHLRWLQQYV AELRLHPEAL NLSLDELPPA LRQDNFSLPS GMALLQQLDT IDNAACGWIQ FMSKVSVDIF KGFPDEESIV NYTLNQAYQD NVTVFASVIF QTRKDGSLPP HVHYKIRQNS SFTEKTNEIR RAYWRPGPNT GGRFYFLYGF VWIQDMMERA IIDTFVGHDV VEPGSYVQMF PYPCYTRDDF LFVIEHMMPL CMVISWVYSV AMTIQHIVAE KEHRLKEVMK TMGLNNAVHW VAWFITGFVQ LSISVTALTA ILKYGQVLMH SHVVIIWLFL AVYAVATIMF CFLVSVLYSK AKLASACGGI IYFLSYVPYM YVAIREEVAH DKITAFEKCI ASLMSTTAFG LGSKYFALYE VAGVGIQWHT FSQSPVEGDD FNLLLAVTML MVDAVVYGIL TWYIEAVHPG MYGLPRPWYF PLQKSYWLGS GRTEAWEWSW PWARTPRLSV MEEDQACAME SRRFEETRGM EEEPTHLPLV VCVDKLTKVY KDDKKLALNK LSLNLYENQV VSFLGHNGAG KTTTMSILTG LFPPTSGSAT IYGHDIRTEM DEIRKNLGMC PQHNVLFDRL TVEEHLWFYS RLKSMAQEEI RREMDKMIED LELSNKRHSL VQTLSGGMKR KLSVAIAFVG GSRAIILDEP TAGVDPYARR AIWDLILKYK PGRTILLSTH HMDEADLLGD RIAIISHGKL KCCGSPLFLK GTYGDGYRLT LVKRPAEPGG PQEPGLASSP PGRAPLSSCS ELQVSQFIRK HVASCLLVSD TSTELSYILP SEAAKKGAFE RLFQHLERSL DALHLSSFGL MDTTLEEVFL KVSEEDQSLE NSEADVKESR KDVLPGAEGP ASGEGHAGNL ARCSELTQSQ ASLQSASSVG SARGDEGAGY TDVYGDYRPL FDNPQDPDNV SLQEVEAEAL SRVGQGSRKL DGGWLKVRQF HGLLVKRFHC ARRNSKALFS QILLPAFFVC VAMTVALSVP EIGDLPPLVL SPSQYHNYTQ PRGNFIPYAN EERREYRLRL SPDASPQQLV STFRLPSGVG ATCVLKSPAN GSLGPTLNLS SGESRLLAAR FFDSMCLESF TQGLPLSNFV PPPPSPAPSD SPASPDEDLQ AWNVSLPPTA GPEMWTSAPS LPRLVREPVR CTCSAQGTGF SCPSSVGGHP PQMRVVTGDI LTDITGHNVS EYLLFTSDRF RLHRYGAITF GNVLKSIPAS FGTRAPPMVR KIAVRRAAQV FYNNKGYHSM PTYLNSLNNA ILRANLPKSK GNPAAYGITV TNHPMNKTSA SLSLDYLLQG TDVVIAIFII VAMSFVPASF VVFLVAEKST KAKHLQFVSG CNPIIYWLAN YVWDMLNYLV PATCCVIILF VFDLPAYTSP TNFPAVLSLF LLYGWSITPI MYPASFWFEV PSSAYVFLIV INLFIGITAT VATFLLQLFE HDKDLKVVNS YLKSCFLIFP NYNLGHGLME MAYNEYINEY YAKIGQFDKM KSPFEWDIVT RGLVAMAVEG VVGFLLTIMC QYNFLRRPQR MPVSTKPVED DVDVASERQR VLRGDADNDM VKIENLTKVY KSRKIGRILA VDRLCLGVRP GECFGLLGVN GAGKTSTFKM LTGDESTTGG EAFVNGHSVL KELLQVQQSL GYCPQCDALF DELTAREHLQ LYTRLRGISW KDEARVVKWA LEKLELTKYA DKPAGTYSGG NKRKLSTAIA LIGYPAFIFL DEPTTGMDPK ARRFLWNLIL DLIKTGRSVV LTSHSMEECE ALCTRLAIMV NGRLRCLGSI QHLKNRFGDG YMITVRTKSS QSVKDVVRFF NRNFPEAMLK ERHHTKVQYQ LKSEHISLAQ VFSKMEQVSG VLGIEDYSVS QTTLDNVFVN FAKKQSDNLE QQETEPPSAL QSPLGCLLSL LRPRSAPTEL RALVADEPED LDTEDEGLIS FEEERAQLSF NTDTLC