Biological process  Transcription ; Cell migration ; Ribosome biogenesis and assembly  Molecular function  Transcription regulator activity   Protein   Treacher Collins-Franceschetti syndrome 1  Gene symbol   TCOF1    Cellular component           Component           Experimental evidence      Total number of studies : 2       Peptide sequence Method Platform  Sample  Reference Mass spectrometry Plasma Liu et al. 2007 Mass spectrometry LTQ FT Serum Sennels et al. 2007          Multiple reaction monitoring data           Peptide sequence MH+ Sample Number of studies Reference Data not present           Protein concentration             Protein concentration Method Sample Reference Data not present           Extracellular vesicle proteins             Sample Isolation  Experimental method Vesiclepedia accession Reference Data not present          Architecture           Domains Motifs LISH   6 - 38 NES   40 - 49 NLS   74 - 77 NLS   1398 - 1405 NLS   1382 - 1385 NLS   1377 - 1380 NLS   1370 - 1375 NLS   1362 - 1365 NLS   1314 - 1317 NLS   1285 - 1289 NLS   1325 - 1328          External links           HPRD UniProt NetPath  06026  Q13428  NetPath_M6949             Protein sequence  NP_000347.2               MAEARKRREL LPLIYHHLLR AGYVRAAREV KEQSGQKCFL AQPVTLLDIY THWQQTSELG RKRKAEEDAA LQAKKTRVSD PISTSESSEE EEEAEAETAK ATPRLASTNS SVLGADLPSS MKEKAKAETE KAGKTGNSMP HPATGKTVAN LLSGKSPRKS AEPSANTTLV SETEEEGSVP AFGAAAKPGM VSAGQADSSS EDTSSSSDET DVEVKASEKI LQVRAASAPA KGTPGKGATP APPGKAGAVA SQTKAGKPEE DSESSSEESS DSEEETPAAK ALLQAKASGK TSQVGAASAP AKESPRKGAA PAPPGKTGPA VAKAQAGKRE EDSQSSSEES DSEEEAPAQA KPSGKAPQVR AASAPAKESP RKGAAPAPPR KTGPAAAQVQ VGKQEEDSRS SSEESDSDRE ALAAMNAAQV KPLGKSPQVK PASTMGMGPL GKGAGPVPPG KVGPATPSAQ VGKWEEDSES SSEESSDSSD GEVPTAVAPA QEKSLGNILQ AKPTSSPAKG PPQKAGPVAV QVKAEKPMDN SESSEESSDS ADSEEAPAAM TAAQAKPALK IPQTKACPKK TNTTASAKVA PVRVGTQAPR KAGTATSPAG SSPAVAGGTQ RPAEDSSSSE ESDSEEEKTG LAVTVGQAKS VGKGLQVKAA SVPVKGSLGQ GTAPVLPGKT GPTVTQVKAE KQEDSESSEE ESDSEEAAAS PAQVKTSVKK TQAKANPAAA RAPSAKGTIS APGKVVTAAA QAKQRSPSKV KPPVRNPQNS TVLARGPASV PSVGKAVATA AQAQTGPEED SGSSEEESDS EEEAETLAQV KPSGKTHQIR AALAPAKESP RKGAAPTPPG KTGPSAAQAG KQDDSGSSSE ESDSDGEAPA AVTSAQVIKP PLIFVDPNRS PAGPAATPAQ AQAASTPRKA RASESTARSS SSESEDEDVI PATQCLTPGI RTNVVTMPTA HPRIAPKASM AGASSSKESS RISDGKKQEG PATQVSKKNP ASLPLTQAAL KVLAQKASEA QPPVARTQPS SGVDSAVGTL PATSPQSTSV QAKGTNKLRK PKLPEVQQAT KAPESSDDSE DSSDSSSGSE EDGEGPQGAK SAHTLGPTPS RTETLVEETA AESSEDDVVA PSQSLLSGYM TPGLTPANSQ ASKATPKLDS SPSVSSTLAA KDDPDGKQEA KPQQAAGMLS PKTGGKEAAS GTTPQKSRKP KKGAGNPQAS TLALQSNITQ CLLGQPWPLN EAQVQASVVK VLTELLEQER KKVVDTTKES SRKGWESRKR KLSGDQPAAR TPRSKKKKKL GAGEGGEASV SPEKTSTTSK GKAKRDKASG DVKEKKGKGS LGSQGAKDEP EEELQKGMGT VEGGDQSNPK SKKEKKKSDK RKKDKEKKEK KKKAKKASTK DSESPSQKKK KKKKKTAEQT V