Biological process  Cell growth and/or maintenance
 Molecular function  Structural constituent of cytoskeleton
 
Protein   actinin, alpha 4  Gene symbol   ACTN4
 
 Cellular component  
     
 
Component
Cytoplasm
Mitochondrion
Nucleus
Plasma membrane
 
   
 
Experimental evidence   
  Total number of studies : 7    
 
Peptide sequence Method Platform  Sample  Reference
Mass spectrometry LTQ Orbitrap Velos Plasma Kalra et al. 2013
Mass spectrometry Plasma Liu et al. 2007
Mass spectrometry LTQ Orbitrap XL Plasma Bassani-Sternberg et al. 2010
Mass spectrometry Fourier transform ion cyclotron resonance (FT_ICR) Plasma Qian et al. 2010
Mass spectrometry LCQ Deca XP Serum Barnea et al. 2005
Mass spectrometry LTQ FT Serum Sennels et al. 2007
Mass spectrometry - Plasma Farrah et al. 2011
 
   
 
 Multiple reaction monitoring data  
     
 
Peptide sequence MH+ Sample Number of studies Reference
Data not present
 
   
 
  Protein concentration    
     
 
Protein concentration Method Sample
Reference
120  ng/ml Spectral counting  Plasma Farrah et al. 2011
 
   
 
  Extracellular vesicle proteins    
     
 
Sample Isolation  Experimental method Vesiclepedia accession Reference
Data not present
 
   
 
 Architecture  
     
 
Domains Motifs
CH   52 - 152
CH   165 - 264
EF   769 - 797
EF   810 - 838
SPECTRIN   293 - 403
SPECTRIN   416 - 517
SPECTRIN   531 - 638
SPECTRIN   649 - 752
CC   447 - 483
 
   
 
 External links  
     
 
HPRD UniProt NetPath 
05222  O43707  NetPath_M81 
 
   
 
 
 Protein sequence  NP_004915.2
     
   
    MVDYHAANQS YQYGPSSAGN GAGGGGSMGD YMAQEDDWDR DLLLDPAWEK QQRKTFTAWC NSHLRKAGTQ IENIDEDFRD GLKLMLLLEV ISGERLPKPE RGKMRVHKIN NVNKALDFIA
SKGVKLVSIG AEEIVDGNAK MTLGMIWTII LRFAIQDISV EETSAKEGLL LWCQRKTAPY KNVNVQNFHI SWKDGLAFNA LIHRHRPELI EYDKLRKDDP VTNLNNAFEV AEKYLDIPKM
LDAEDIVNTA RPDEKAIMTY VSSFYHAFSG AQKAETAANR ICKVLAVNQE NEHLMEDYEK LASDLLEWIR RTIPWLEDRV PQKTIQEMQQ KLEDFRDYRR VHKPPKVQEK CQLEINFNTL
QTKLRLSNRP AFMPSEGKMV SDINNGWQHL EQAEKGYEEW LLNEIRRLER LDHLAEKFRQ KASIHEAWTD GKEAMLKHRD YETATLSDIK ALIRKHEAFE SDLAAHQDRV EQIAAIAQEL
NELDYYDSHN VNTRCQKICD QWDALGSLTH SRREALEKTE KQLEAIDQLH LEYAKRAAPF NNWMESAMED LQDMFIVHTI EEIEGLISAH DQFKSTLPDA DREREAILAI HKEAQRIAES
NHIKLSGSNP YTTVTPQIIN SKWEKVQQLV PKRDHALLEE QSKQQSNEHL RRQFASQANV VGPWIQTKME EIGRISIEMN GTLEDQLSHL KQYERSIVDY KPNLDLLEQQ HQLIQEALIF
DNKHTNYTME HIRVGWEQLL TTIARTINEV ENQILTRDAK GISQEQMQEF RASFNHFDKD HGGALGPEEF KACLISLGYD VENDRQGEAE FNRIMSLVDP NHSGLVTFQA FIDFMSRETT
DTDTADQVIA SFKVLAGDKN FITAEELRRE LPPDQAEYCI ARMAPYQGPD AVPGALDYKS FSTALYGESD L