Biological process  Transport ; Lipid metabolism
 Molecular function  Lipid transporter activity
 
Protein   apolipoprotein L, 1  Gene symbol   APOL1
 
 Cellular component  
     
 
Component
Extracellular
 
   
 
Experimental evidence   
  Total number of studies : 22    
 
Peptide sequence Method Platform  Sample  Reference
Mass spectrometry LTQ Plasma Looze et al. 2008
Mass spectrometry Q-TOF Plasma Bastos-Amador et al. 2012
Mass spectrometry LTQ Orbitrap Velos Plasma Kalra et al. 2013
Multiple reaction monitoring 6490 QQQ Plasma Domanski et al. 2012
Multiple reaction monitoring 6490 QQQ Plasma Percy et al. 2012
Multiple reaction monitoring TSQ Quantum Ultra Plasma Ahn et al. 2012
Mass spectrometry Plasma Liu et al. 2007
Mass spectrometry LCQ Duo Serum Gundry et al. 2007
Mass spectrometry LTQ Plasma Carrascal et al. 2009
Mass spectrometry QSTAR Pulsar Serum Zhou et al. 2004
Mass spectrometry LTQ FT Serum Zheng et al. 2006
Mass spectrometry LTQ Orbitrap XL Plasma Madian et al. 2010
Mass spectrometry Fourier transform ion cyclotron resonance (FT_ICR) Plasma Qian et al. 2010
Mass spectrometry LTQ Orbitrap XL Plasma Panchaud et al. 2009
Mass spectrometry LTQ Orbitrap XL Plasma Kang et al. 2010
Mass spectrometry - Plasma Michel et al. 2006
Mass spectrometry Finnigan LTQ MS Plasma Okano et al. 2006
Mass spectrometry LTQ FT Serum Sennels et al. 2007
Mass spectrometry LTQ Plasma Tu et al. 2010
Mass spectrometry LTQ Orbitrap Plasma Shuford et al. 2010
Mass spectrometry LTQ Orbitrap XL Serum Sinclair et al. 2011
Mass spectrometry - Plasma Farrah et al. 2011
 
   
 
 Multiple reaction monitoring data  
     
 
Peptide sequence MH+ Sample Number of studies Reference
VTEPISAESGEQVER  1636.8  Plasma  Domanski et al. 2012
VTEPISAESGEQVER  1630.8  Plasma  Domanski et al. 2012
VTEPISAESGEQVER  1630.8  Plasma  Percy et al. 2012
WWTQAQAHDLVIK  1595.8  Plasma  Percy et al. 2012
VTEPISAESGEQVER  1630.7  Plasma  Domanski et al. 2012
WWTQAQAHDLVIK  1595.8  Plasma  Domanski et al. 2012
LNILNNNYK  1111.6  Plasma  Domanski et al. 2012
LNILNNNYK  1105.6  Plasma  Domanski et al. 2012
LNILNNNYK  1105.6  Plasma  Percy et al. 2012
VTEPISAESGEQVER  1630.8  Plasma  Ahn et al. 2012
VTEPISAESGEQVER  1636.8  Plasma  Ahn et al. 2012
 
   
 
  Protein concentration    
     
 
Protein concentration Method Sample
Reference
5.9  μg/ml Plasma Gundry et al. 2007
1.2  μg/ml Spectral counting  Plasma Farrah et al. 2011
 
   
 
  Extracellular vesicle proteins    
     
 
Sample Isolation  Experimental method Vesiclepedia accession Reference
Plasma - Normal  Filtration|Size exclusion|Sucrose density gradient  Mass spectrometry [LTQ]|Western blotting|Immunoelectron Microscopy  Vesiclepedia_8542 Bastos-Amador et al. 2012 
Plasma  Differential centrifugation|Filtration|Ultracenrifugation|Sucrose density gradient  Mass spectrometry [Q-TOF]  Vesiclepedia_8542 Bastos-Amador et al. 2012 
 
   
 
 Architecture  
     
 
Domains Motifs
CC   376 - 414
SP   1 - 43
 
   
 
 External links  
     
 
HPRD UniProt NetPath 
04774  O14791  NetPath_M8542 
 
   
 
 
 Protein sequence  NP_663318.1
     
   
    MRFKSHTVEL RRPCSDMEGA ALLRVSVLCI WMSALFLGVG VRAEEAGARV QQNVPSGTDT GDPQSKPLGD WAAGTMDPES SIFIEDAIKY FKEKVSTQNL LLLLTDNEAW NGFVAAAELP
RNEADELRKA LDNLARQMIM KDKNWHDKGQ QYRNWFLKEF PRLKSELEDN IRRLRALADG VQKVHKGTTI ANVVSGSLSI SSGILTLVGM GLAPFTEGGS LVLLEPGMEL GITAALTGIT
SSTMDYGKKW WTQAQAHDLV IKSLDKLKEV REFLGENISN FLSLAGNTYQ LTRGIGKDIR ALRRARANLQ SVPHASASRP RVTEPISAES GEQVERVNEP SILEMSRGVK LTDVAPVSFF
LVLDVVYLVY ESKHLHEGAK SETAEELKKV AQELEEKLNI LNNNYKILQA DQEL