Biological process  Protein metabolism
 Molecular function  Metallopeptidase activity
 
Protein   ADAM metallopeptidase domain 8  Gene symbol   ADAM8
 
 Cellular component  
     
 
Component
Plasma membrane
 
   
 
Experimental evidence   
  Total number of studies : 3    
 
Peptide sequence Method Platform  Sample  Reference
ELISA - Serum Ishikawa et al. 2004
Mass spectrometry LTQ linear ion trap Plasma Jin et al. 2005
Mass spectrometry - Plasma Farrah et al. 2011
 
   
 
 Multiple reaction monitoring data  
     
 
Peptide sequence MH+ Sample Number of studies Reference
Data not present
 
   
 
  Protein concentration    
     
 
Protein concentration Method Sample
Reference
267+/-56  pg/ml ELISA  Serum Ishikawa et al. 2004
 
   
 
  Extracellular vesicle proteins    
     
 
Sample Isolation  Experimental method Vesiclepedia accession Reference
Data not present
 
   
 
 Architecture  
     
 
Domains Motifs
ACR   493 - 605
DISINT   417 - 492
EGF   612 - 641
REP   200 - 400
TM   656 - 678
SP   1 - 20
 
   
 
 External links  
     
 
HPRD UniProt NetPath 
03777  P78325  NetPath_M101 
 
   
 
 
 Protein sequence  NP_001100.3
     
   
    MRGLGLWLLG AMMLPAIAPS RPWALMEQYE VVLPWRLPGP RVRRALPSHL GLHPERVSYV LGATGHNFTL HLRKNRDLLG SGYTETYTAA NGSEVTEQPR GQDHCFYQGH VEGYPDSAAS
LSTCAGLRGF FQVGSDLHLI EPLDEGGEGG RHAVYQAEHL LQTAGTCGVS DDSLGSLLGP RTAAVFRPRP GDSLPSRETR YVELYVVVDN AEFQMLGSEA AVRHRVLEVV NHVDKLYQKL
NFRVVLVGLE IWNSQDRFHV SPDPSVTLEN LLTWQARQRT RRHLHDNVQL ITGVDFTGTT VGFARVSAMC SHSSGAVNQD HSKNPVGVAC TMAHEMGHNL GMDHDENVQG CRCQERFEAG
RCIMAGSIGS SFPRMFSDCS QAYLESFLER PQSVCLANAP DLSHLVGGPV CGNLFVERGE QCDCGPPEDC RNRCCNSTTC QLAEGAQCAH GTCCQECKVK PAGELCRPKK DMCDLEEFCD
GRHPECPEDA FQENGTPCSG GYCYNGACPT LAQQCQAFWG PGGQAAEESC FSYDILPGCK ASRYRADMCG VLQCKGGQQP LGRAICIVDV CHALTTEDGT AYEPVPEGTR CGPEKVCWKG
RCQDLHVYRS SNCSAQCHNH GVCNHKQECH CHAGWAPPHC AKLLTEVHAA SGSLPVFVVV VLVLLAVVLV TLAGIIVYRK ARSRILSRNV APKTTMGRSN PLFHQAASRV PAKGGAPAPS
RGPQELVPTT HPGQPARHPA SSVALKRPPP APPVTVSSPP FPVPVYTRQA PKQVIKPTFA PPVPPVKPGA GAANPGPAEG AVGPKVALKP PIQRKQGAGA PTAP