Biological process  Transport
 Molecular function  Transporter activity
 
Protein   apolipoprotein A-I  Gene symbol   APOA1
 
 Cellular component  
     
 
Component
Cytoplasm
Extracellular
Golgi apparatus
 
   
 
Experimental evidence   
  Total number of studies : 65    
 
Peptide sequence Method Platform  Sample  Reference
ELISA - Serum Kurtz et al. 2004
Immunoassay - Plasma Haab et al. 2005
Immunoturbidometry - Serum Glowinska et al. 2003
Mass spectrometry LTQ-Orbitrap Plasma Schenk et al. 2008
Mass spectrometry Q-TOF Plasma Bastos-Amador et al. 2012
Mass spectrometry LTQ Orbitrap Velos Plasma Kalra et al. 2013
Multiple reaction monitoring - Plasma Percy et al. 2012
Multiple reaction monitoring 4000 QTRAP Plasma Randall et al. 2010
Multiple reaction monitoring 6490 QQQ Plasma Percy et al. 2013
Multiple reaction monitoring 6490 QQQ Blood Chambers et al. 2012
Multiple reaction monitoring 6490 QQQ Plasma Domanski et al. 2012
Multiple reaction monitoring 6490 QQQ Plasma Percy et al. 2012
Multiple reaction monitoring 4000 QTRAP Plasma Agger et al. 2010
Multiple reaction monitoring 4000 QTRAP Plasma Kuzyk et al. 2009
Multiple reaction monitoring TSQ Vantage Plasma Huttenhain et al. 2012
Multiple reaction monitoring 4000 QTRAP Plasma Barton et al. 2009
Multiple reaction monitoring 4000 QTRAP Serum Kay et al. 2007
Multiple reaction monitoring 4000 QTRAP Plasma Hoofnagle et al. 2012
Mass spectrometry LCQ DecaXP Serum Tirumalai et al. 2003
Mass spectrometry Plasma Liu et al. 2007
Mass spectrometry LCQ Duo Serum Gundry et al. 2007
Mass spectrometry 4800 Plus MALDI TOF/TOF Plasma Madian et al. 2010
Mass spectrometry LTQ Plasma Carrascal et al. 2009
Mass spectrometry QSTAR Pulsar Serum Zhou et al. 2004
Mass spectrometry LTQ Orbitrap XL Plasma Madian et al. 2010
Mass spectrometry API QSTAR Pulsar i Plasma Wasinger et al. 2005
Mass spectrometry LCQ Deca XP Plus Serum Adkins et al. 2003
Mass spectrometry Plasma Zhang et al. 2010
Mass spectrometry Fourier transform ion cyclotron resonance (FT_ICR) Plasma Qian et al. 2010
Mass spectrometry LTQ Orbitrap XL Plasma Panchaud et al. 2009
Mass spectrometry 6340 Ion Trap LC/MS Plasma Zhang et al. 2008
Mass spectrometry LTQ Orbitrap XL Plasma Kang et al. 2010
2-D DIGE - Plasma Corzett et al. 2010
Mass spectrometry MALDI-TOF Plasma Chen et al. 2004
Mass spectrometry Fourier transform ion cyclotron resonance (FT_ICR) Plasma Qian et al. 2005
Mass spectrometry LTQ linear ion trap Plasma Jin et al. 2005
Mass spectrometry MALDI-TOF Plasma Nedelkov et al. 2005
Mass spectrometry LCQ Deca XP Serum Barnea et al. 2005
Mass spectrometry LTQ linear ion trap Serum He et al. 2005
Mass spectrometry LCQ Deca Plasma Moritz et al. 2005
Mass spectrometry LTQ linear ion trap Plasma Tu et al. 2005
Mass spectrometry - Plasma Michel et al. 2006
Mass spectrometry MALDI-TOF Plasma Yang et al. 2006
Mass spectrometry Finnigan LTQ MS Plasma Okano et al. 2006
Mass spectrometry IMS-TOF Plasma Valentine et al. 2006
Mass spectrometry MALDI-TOF Plasma Manabe et al. 2007
Mass spectrometry Finnigan LTQ MS Plasma Kakisaka et al. 2007
Mass spectrometry IMS-TOF Plasma Manabe et al. 2007
Mass spectrometry LTQ FT Serum Sennels et al. 2007
Mass spectrometry SELDI-TOF Plasma Sihlbom et al. 2008
Mass spectrometry Agilent XCT plus Serum Stempfer et al. 2008
Mass spectrometry LTQ-Orbitrap Plasma Greening et al. 2009
Mass spectrometry Agilent 1100 LC/MSD Trap XCT Plus System Plasma Ahrends et al. 2009
Mass spectrometry 4800 Plus MALDI TOF/TOF Plasma Kolla et al. 2009
Mass spectrometry 4800 Plus MALDI TOF/TOF Plasma Jeong et al. 2010
Mass spectrometry MALDI-TOF Serum Wong et al. 2010
Mass spectrometry MALDI-TOF Plasma Darde et al. 2010
Mass spectrometry LTQ Plasma Tu et al. 2010
Mass spectrometry LTQ Orbitrap Plasma Shuford et al. 2010
Mass spectrometry 1100 Series LC/MSD Trap XCT Ultra ion trap Plasma Kaur et al. 2010
Mass spectrometry MALDI-TOF/TOF Plasma Bortner et al. 2010
Mass spectrometry LTQ Orbitrap XL Serum Sinclair et al. 2011
Mass spectrometry 4800 Proteomics Analyzer Plasma Bouwman et al. 2011
Mass spectrometry - Plasma Farrah et al. 2011
Mass spectrometry LCQ Deca XP Plus Plasma/Serum Yang et al. 2005
Mass spectrometry LCQ DECA XP Serum Yang et al. 2004
 
   
 
 Multiple reaction monitoring data  
     
 
Peptide sequence MH+ Sample Number of studies Reference
ATEHLSTLSEK  1214.6  Plasma  Kuzyk et al. 2009
ATEHLSTLSEK  1221.6  Plasma  Domanski et al. 2012
ATEHLSTLSEK  1215.6  Plasma  Domanski et al. 2012
ATEHLSTLSEK  1215.6  Plasma  Percy et al. 2012
ATEHLSTLSEK  1215.6  Blood  Chambers et al. 2012
ATEHLSTLSEK  1215.6  Plasma  Percy et al. 2013
VQPYLDDFQK  1252.6  Plasma  Percy et al. 2013
DYVSQFEGSALGK  1399.6  Serum  Kay et al. 2007
LLDNWDSVTSTFSK  1612.8  Plasma  McKay et al. 2007
VSFLSALEEYTK  1386.7  Plasma  McKay et al. 2007
AKPALEDLR  1012.5  Plasma  McKay et al. 2007
DLATVYVDVLK  1235.7  Plasma  Huttenhain et al. 2012
DYVSQFEGSALGK  1400.6  Plasma  Huttenhain et al. 2012
VSFLSALEEYTK  1386.7  Plasma  Huttenhain et al. 2012
VQPYLDDFQK  1252.6  Plasma  Hoofnagle et al. 2012
VQPYLDDFQK  1258.6  Plasma  Hoofnagle et al. 2012
VQPYLDDFQK  1252.6  Plasma  Agger et al. 2010
DYVSQFEGSALGK  1400.6  Plasma  Agger et al. 2010
LLDNWDSVTSTFSK  1612.8  Plasma  Agger et al. 2010
ATEHLSTLSEK  1215.6  Plasma  Agger et al. 2010
DYVSQFEGSALGK  1400.6  Plasma  Barton et al. 2009
THLAPYSDELR  1301.6  Plasma  Randall et al. 2010
ATEHLSTLSEK  1215.6  Plasma  Randall et al. 2010
DLATVYVDVLK  1235.6  Plasma  Randall et al. 2010
AKPALEDLR  1012.5  Plasma  Randall et al. 2010
QGLLPVLESFK  1230.7  Plasma  Randall et al. 2010
VQPYLDDFQK  1252.6  Plasma  Randall et al. 2010
DYVSQFEGSALGK  1400.6  Plasma  Randall et al. 2010
DLATVYVDVLK  1235.6  Plasma  Percy et al. 2013
 
   
 
  Protein concentration    
     
 
Protein concentration Method Sample
Reference
310  μg/ml Spectral counting  Plasma Farrah et al. 2011
900.8  μg/ml Multiple reaction monitoring  Plasma Percy et al. 2012
1079.45  μg/ml Multiple reaction monitoring  Blood Chambers et al. 2012
1100  μg/ml Multiple reaction monitoring  Plasma Percy et al. 2012
1330  μg/ml Multiple reaction monitoring  Plasma Domanski et al. 2012
1375  mg/ml Plasma Qian et al. 2005
1400  μg/ml Plasma Anderson et al. 2004
1400  μg/ml Immunoassay  Plasma Haab et al. 2005
1400  μg/ml Plasma Panchaud et al. 2009
1400  μg/ml Plasma Polanski et al. 2007
1400  μg/ml Plasma Gundry et al. 2007
1400  μg/ml Plasma Tu et al. 2010
1500  μg/ml Plasma Wu et al. 2003
135.6+/-17  mg/dl Immunoturbidometry  Serum Glowinska et al. 2003
670-2200  μg/ml ELISA  Serum Kurtz et al. 2004
 
   
 
  Extracellular vesicle proteins    
     
 
Sample Isolation  Experimental method Vesiclepedia accession Reference
Plasma  Differential centrifugation|Filtration|Ultracenrifugation|Sucrose density gradient  Mass spectrometry [Q-TOF]  Vesiclepedia_335 Bastos-Amador et al. 2012 
 
   
 
 Architecture  
     
 
Domains Motifs
CC   130 - 157
SP   1 - 19
 
   
 
 External links  
     
 
HPRD UniProt NetPath 
02517  P02647  NetPath_M335 
 
   
 
 
 Protein sequence  NP_000030.1
     
   
    MKAAVLTLAV LFLTGSQARH FWQQDEPPQS PWDRVKDLAT VYVDVLKDSG RDYVSQFEGS ALGKQLNLKL LDNWDSVTST FSKLREQLGP VTQEFWDNLE KETEGLRQEM SKDLEEVKAK
VQPYLDDFQK KWQEEMELYR QKVEPLRAEL QEGARQKLHE LQEKLSPLGE EMRDRARAHV DALRTHLAPY SDELRQRLAA RLEALKENGG ARLAEYHAKA TEHLSTLSEK AKPALEDLRQ
GLLPVLESFK VSFLSALEEY TKKLNTQ