Biological process  Cell growth and/or maintenance
 Molecular function  Extracellular matrix structural constituent
 
Protein   TIMP metallopeptidase inhibitor 1  Gene symbol   TIMP1
 
 Cellular component  
     
 
Component
Cell surface
Extracellular
 
   
 
Experimental evidence   
  Total number of studies : 13    
 
Peptide sequence Method Platform  Sample  Reference
ELISA - Serum Higashimoto et al. 2008
ELISA - Serum Hastbacka et al. 2011
Immunoassay - Plasma Haab et al. 2005
Sandwich enzyme Immunoassay - Plasma Noji et al. 2001
Multiple reaction monitoring TSQ Vantage Plasma Huttenhain et al. 2012
Mass spectrometry LTQ FT Plasma Jia et al. 2009
Mass spectrometry LCQ Deca XP Plus Plasma Gong et al. 2006
Mass spectrometry Fourier transform ion cyclotron resonance (FT_ICR) Plasma Qian et al. 2010
Mass spectrometry LTQ Orbitrap XL Plasma Panchaud et al. 2009
Mass spectrometry Q-TOF Plasma Xiao et al. 2005
Mass spectrometry LTQ FT Plasma Prentice et al. 2010
Mass spectrometry 4800 Proteomics Analyzer Plasma Bouwman et al. 2011
Mass spectrometry - Plasma Farrah et al. 2011
 
   
 
 Multiple reaction monitoring data  
     
 
Peptide sequence MH+ Sample Number of studies Reference
FVGTPEVNQTTLYQR  1752.9  Plasma  Huttenhain et al. 2012
GFQALGDAADIR  1233.6  Plasma  Huttenhain et al. 2012
 
   
 
  Protein concentration    
     
 
Protein concentration Method Sample
Reference
14  ng/ml Immunoassay  Plasma Haab et al. 2005
14  ng/ml Plasma Liu et al. 2005
14  ng/ml Plasma Panchaud et al. 2009
95  ng/ml Plasma Anderson et al. 2004
95  ng/ml Plasma Polanski et al. 2007
270  ng/ml Spectral counting  Plasma Farrah et al. 2011
143+/-8  ng/ml ELISA  Serum Higashimoto et al. 2008
56.99-73.59  ng/ml Plasma Janciauskiene et al. 2010
80.75-129.25  ng/ml ELISA  Serum Hastbacka et al. 2011
94.5+/-26.3  ng/ml Sandwich enzyme Immunoassay  Plasma Noji et al. 2001
 
   
 
  Extracellular vesicle proteins    
     
 
Sample Isolation  Experimental method Vesiclepedia accession Reference
Data not present
 
   
 
 Architecture  
     
 
Domains Motifs
C345C   24 - 199
SP   1 - 23
 
   
 
 External links  
     
 
HPRD UniProt NetPath 
02371  P01033  NetPath_M7076 
 
   
 
 
 Protein sequence  NP_003245.1
     
   
    MAPFEPLASG ILLLLWLIAP SRACTCVPPH PQTAFCNSDL VIRAKFVGTP EVNQTTLYQR YEIKMTKMYK GFQALGDAAD IRFVYTPAME SVCGYFHRSH NRSEEFLIAG KLQDGLLHIT
TCSFVAPWNS LSLAQRRGFT KTYTVGCEEC TVFPCLSIPC KLQSGTHCLW TDQLLQGSEK GFQSRHLACL PREPGLCTWQ SLRSQIA