Biological process  Innate immune response
 Molecular function  Receptor activity
 
Protein   toll-like receptor 8  Gene symbol   TLR8
 
 Cellular component  
     
 
Component
 
 
   
 
Experimental evidence   
  Total number of studies : 1    
 
Peptide sequence Method Platform  Sample  Reference
Mass spectrometry Plasma Liu et al. 2007
 
   
 
 Multiple reaction monitoring data  
     
 
Peptide sequence MH+ Sample Number of studies Reference
Data not present
 
   
 
  Protein concentration    
     
 
Protein concentration Method Sample
Reference
Data not present
 
   
 
  Extracellular vesicle proteins    
     
 
Sample Isolation  Experimental method Vesiclepedia accession Reference
Data not present
 
   
 
 Architecture  
     
 
Domains Motifs
LRR   790 - 841
LRR   753 - 776
LRR   729 - 752
LRR   705 - 728
LRR   656 - 679
LRR   601 - 623
LRR   435 - 458
LRR   411 - 434
LRR   384 - 407
LRR   354 - 378
LRR   328 - 352
LRR   304 - 327
LRR   242 - 262
LRR   218 - 241
LRR   142 - 165
LRR   84 - 103
TIR   897 - 1043
TM   844 - 866
SP   1 - 45
 
   
 
 External links  
     
 
HPRD UniProt NetPath 
02296  Q9NR97  NetPath_M51311 
 
   
 
 
 Protein sequence  NP_057694.2
     
   
    MKESSLQNSS CSLGKETKKE NMFLQSSMLT CIFLLISGSC ELCAEENFSR SYPCDEKKQN DSVIAECSNR RLQEVPQTVG KYVTELDLSD NFITHITNES FQGLQNLTKI NLNHNPNVQH
QNGNPGIQSN GLNITDGAFL NLKNLRELLL EDNQLPQIPS GLPESLTELS LIQNNIYNIT KEGISRLINL KNLYLAWNCY FNKVCEKTNI EDGVFETLTN LELLSLSFNS LSHVPPKLPS
SLRKLFLSNT QIKYISEEDF KGLINLTLLD LSGNCPRCFN APFPCVPCDG GASINIDRFA FQNLTQLRYL NLSSTSLRKI NAAWFKNMPH LKVLDLEFNY LVGEIASGAF LTMLPRLEIL
DLSFNYIKGS YPQHINISRN FSKLLSLRAL HLRGYVFQEL REDDFQPLMQ LPNLSTINLG INFIKQIDFK LFQNFSNLEI IYLSENRISP LVKDTRQSYA NSSSFQRHIR KRRSTDFEFD
PHSNFYHFTR PLIKPQCAAY GKALDLSLNS IFFIGPNQFE NLPDIACLNL SANSNAQVLS GTEFSAIPHV KYLDLTNNRL DFDNASALTE LSDLEVLDLS YNSHYFRIAG VTHHLEFIQN
FTNLKVLNLS HNNIYTLTDK YNLESKSLVE LVFSGNRLDI LWNDDDNRYI SIFKGLKNLT RLDLSLNRLK HIPNEAFLNL PASLTELHIN DNMLKFFNWT LLQQFPRLEL LDLRGNKLLF
LTDSLSDFTS SLRTLLLSHN RISHLPSGFL SEVSSLKHLD LSSNLLKTIN KSALETKTTT KLSMLELHGN PFECTCDIGD FRRWMDEHLN VKIPRLVDVI CASPGDQRGK SIVSLELTTC
VSDVTAVILF FFTFFITTMV MLAALAHHLF YWDVWFIYNV CLAKVKGYRS LSTSQTFYDA YISYDTKDAS VTDWVINELR YHLEESRDKN VLLCLEERDW DPGLAIIDNL MQSINQSKKT
VFVLTKKYAK SWNFKTAFYL ALQRLMDENM DVIIFILLEP VLQHSQYLRL RQRICKSSIL QWPDNPKAEG LFWQTLRNVV LTENDSRYNN MYVDSIKQY