Biological process  Protein metabolism  Molecular function  Protease inhibitor activity   Protein   kininogen 1  Gene symbol   KNG1    Cellular component           Component Extracellular         Experimental evidence      Total number of studies : 54       Peptide sequence Method Platform  Sample  Reference Mass spectrometry Q-TOF Plasma Bastos-Amador et al. 2012 Mass spectrometry LTQ Orbitrap Velos Plasma Kalra et al. 2013 Multiple reaction monitoring - Plasma Percy et al. 2012 Multiple reaction monitoring - Plasma Percy et al. 2013 Multiple reaction monitoring 6490 QQQ Plasma Percy et al. 2013 Multiple reaction monitoring 4000 QTRAP Plasma Randall et al. 2010 Multiple reaction monitoring 6490 QQQ Blood Chambers et al. 2012 Multiple reaction monitoring 4000 QTRAP Plasma Kuzyk et al. 2009 Mass spectrometry LCQ DecaXP Serum Tirumalai et al. 2003 Mass spectrometry Plasma Liu et al. 2007 Mass spectrometry Q-TOF Ultima Plasma Hagglund et al. 2007 Mass spectrometry LCQ Duo Serum Gundry et al. 2007 Mass spectrometry LTQ Orbitrap XL Plasma Bassani-Sternberg et al. 2010 Mass spectrometry LTQ FT Plasma Jia et al. 2009 Mass spectrometry LTQ Plasma Carrascal et al. 2009 Mass spectrometry LCQ Deca XP Plus Serum Adkins et al. 2003 Mass spectrometry API QSTAR Pulsar i Plasma Wasinger et al. 2005 Mass spectrometry LTQ FT Serum Zheng et al. 2006 Mass spectrometry LTQ Orbitrap XL Plasma Madian et al. 2010 Mass spectrometry Fourier transform ion cyclotron resonance (FT_ICR) Plasma Qian et al. 2010 Mass spectrometry LTQ Orbitrap XL Plasma Panchaud et al. 2009 Mass spectrometry 6340 Ion Trap LC/MS Plasma Zhang et al. 2008 Mass spectrometry LTQ Orbitrap XL Plasma Kang et al. 2010 2-D DIGE - Plasma Corzett et al. 2010 Mass spectrometry Finnigan LTQ MS Plasma Fujii et al. 2005 Mass spectrometry Fourier transform ion cyclotron resonance (FT_ICR) Plasma Qian et al. 2005 Mass spectrometry LTQ linear ion trap Plasma Jin et al. 2005 Mass spectrometry MALDI-TOF/TOF Serum Misek et al. 2005 Mass spectrometry LCQ Deca XP Serum Barnea et al. 2005 Mass spectrometry LTQ linear ion trap Serum He et al. 2005 Mass spectrometry LCQ Deca Plasma Moritz et al. 2005 Mass spectrometry LTQ linear ion trap Plasma Tu et al. 2005 Mass spectrometry - Plasma Michel et al. 2006 Mass spectrometry IMS-TOF Plasma Valentine et al. 2006 Mass spectrometry MALDI-TOF Plasma Manabe et al. 2007 Mass spectrometry IMS-TOF Plasma Manabe et al. 2007 Mass spectrometry LTQ FT Serum Sennels et al. 2007 Mass spectrometry Finnigan LTQ MS Plasma Dayarathna et al. 2008 Mass spectrometry LTQ-Orbitrap Plasma Greening et al. 2009 Mass spectrometry Agilent 1100 LC/MSD Trap XCT Plus System Plasma Ahrends et al. 2009 Mass spectrometry 4800 Plus MALDI TOF/TOF Plasma Jeong et al. 2010 Mass spectrometry MALDI-TOF Plasma Darde et al. 2010 Mass spectrometry LTQ FT Plasma Prentice et al. 2010 Mass spectrometry LTQ Plasma Tu et al. 2010 Mass spectrometry MALDI-TOF Plasma Kolialexi et al. 2010 Mass spectrometry LTQ Orbitrap Plasma Shuford et al. 2010 Mass spectrometry MALDI-TOF/TOF Plasma Bortner et al. 2010 Mass spectrometry MALDI-TOF/TOF Plasma Ignjatovic et al. 2011 Mass spectrometry LTQ Orbitrap Plasma Peng et al. 2011 Mass spectrometry LTQ Orbitrap XL Serum Sinclair et al. 2011 Mass spectrometry - Plasma Farrah et al. 2011 Mass Spectrometry LTQ Plasma Kullolli et al. 2009 Mass spectrometry LCQ Deca XP Plus Plasma/Serum Yang et al. 2005 Mass spectrometry LCQ DECA XP Serum Yang et al. 2004          Multiple reaction monitoring data           Peptide sequence MH+ Sample Number of studies Reference DIPTNSPELEETLTHTITK  2139  Plasma  2  Percy et al. 2013 TVGSDTFYSFK  1250.6  Plasma  1  Kuzyk et al. 2009 QVVAGLNFR  1003.5  Plasma  1  Randall et al. 2010 YFIDFVAR  1030.5  Plasma  1  Randall et al. 2010 DIPTNSPELEETLTHTITK  2139  Plasma  2  Randall et al. 2010 TVGSDTFYSFK  1251.5  Blood  1  Chambers et al. 2012           Protein concentration             Protein concentration Method Sample Reference 28  μg/ml Spectral counting  Plasma Farrah et al. 2011 61  μg/ml -  Serum Gundry et al. 2007 70  μg/ml -  Plasma Qian et al. 2005 70  μg/ml -  Plasma Tu et al. 2010 82.39  μg/ml Multiple reaction monitoring  Blood Chambers et al. 2012 90  μg/ml -  Plasma Qian et al. 2005 90  μg/ml -  Plasma Tu et al. 2010 120  μg/ml -  Plasma Wu et al. 2003 133  μg/ml Multiple reaction monitoring  Plasma Percy et al. 2012 1085  μg/ml Multiple reaction monitoring  Plasma Percy et al. 2013           Extracellular vesicle proteins             Sample Isolation  Experimental method Vesiclepedia accession Reference Plasma  Differential centrifugation|Filtration|Ultracenrifugation|Sucrose density gradient  Mass spectrometry [Q-TOF]  Vesiclepedia_3827 Bastos-Amador et al. 2012           Architecture           Domains Motifs CYSTATIN   25 - 127 CYSTATIN   141 - 249 CYSTATIN   263 - 371 SP   1 - 24          External links           HPRD UniProt NetPath  01970  P01042  NetPath_M3827             Protein sequence  NP_000884.1               MKLITILFLC SRLLLSLTQE SQSEEIDCND KDLFKAVDAA LKKYNSQNQS NNQFVLYRIT EATKTVGSDT FYSFKYEIKE GDCPVQSGKT WQDCEYKDAA KAATGECTAT VGKRSSTKFS VATQTCQITP AEGPVVTAQY DCLGCVHPIS TQSPDLEPIL RHGIQYFNNN TQHSSLFMLN EVKRAQRQVV AGLNFRITYS IVQTNCSKEN FLFLTPDCKS LWNGDTGECT DNAYIDIQLR IASFSQNCDI YPGKDFVQPP TKICVGCPRD IPTNSPELEE TLTHTITKLN AENNATFYFK IDNVKKARVQ VVAGKKYFID FVARETTCSK ESNEELTESC ETKKLGQSLD CNAEVYVVPW EKKIYPTVNC QPLGMISLMK RPPGFSPFRS SRIGEIKEET TSHLRSCEYK GRPPKAGAEP ASEREVS