Biological process  Cell communication ; Signal transduction  Molecular function  Transmembrane receptor protein tyrosine kinase activity   Protein   kinase insert domain receptor (a type III receptor tyrosine kinase)  Gene symbol   KDR    Cellular component           Component Plasma membrane         Experimental evidence      Total number of studies : 4       Peptide sequence Method Platform  Sample  Reference ELISA - Serum Robak et al. 2004 ELISA - Plasma Trelinski et al. 2010 ELISA - Plasma Trelinski et al. 2010 Mass spectrometry Plasma Liu et al. 2007          Multiple reaction monitoring data           Peptide sequence MH+ Sample Number of studies Reference Data not present           Protein concentration             Protein concentration Method Sample Reference 15  ng/ml -  Plasma Polanski et al. 2007 5.5-11.4  ng/ml ELISA  Plasma Trelinski et al. 2010 5.555-11.37  ng/ml ELISA  Plasma Trelinski et al. 2010 8.7-26  ng/ml ELISA  Serum Robak et al. 2004           Extracellular vesicle proteins             Sample Isolation  Experimental method Vesiclepedia accession Reference Data not present          Architecture           Domains Motifs IGC2   343 - 405 IGC2   679 - 744 Ig_LIKE   38 - 119 Ig_LIKE   135 - 218 Ig_LIKE   237 - 325 Ig_LIKE   436 - 548 Ig_LIKE   562 - 662 TM   763 - 785 Tyr_Kinase   834 - 1160 SP   1 - 18          External links           HPRD UniProt NetPath  01867  P35968  NetPath_M3791             Protein sequence  NP_002244.1               MQSKVLLAVA LWLCVETRAA SVGLPSVSLD LPRLSIQKDI LTIKANTTLQ ITCRGQRDLD WLWPNNQSGS EQRVEVTECS DGLFCKTLTI PKVIGNDTGA YKCFYRETDL ASVIYVYVQD YRSPFIASVS DQHGVVYITE NKNKTVVIPC LGSISNLNVS LCARYPEKRF VPDGNRISWD SKKGFTIPSY MISYAGMVFC EAKINDESYQ SIMYIVVVVG YRIYDVVLSP SHGIELSVGE KLVLNCTART ELNVGIDFNW EYPSSKHQHK KLVNRDLKTQ SGSEMKKFLS TLTIDGVTRS DQGLYTCAAS SGLMTKKNST FVRVHEKPFV AFGSGMESLV EATVGERVRI PAKYLGYPPP EIKWYKNGIP LESNHTIKAG HVLTIMEVSE RDTGNYTVIL TNPISKEKQS HVVSLVVYVP PQIGEKSLIS PVDSYQYGTT QTLTCTVYAI PPPHHIHWYW QLEEECANEP SQAVSVTNPY PCEEWRSVED FQGGNKIEVN KNQFALIEGK NKTVSTLVIQ AANVSALYKC EAVNKVGRGE RVISFHVTRG PEITLQPDMQ PTEQESVSLW CTADRSTFEN LTWYKLGPQP LPIHVGELPT PVCKNLDTLW KLNATMFSNS TNDILIMELK NASLQDQGDY VCLAQDRKTK KRHCVVRQLT VLERVAPTIT GNLENQTTSI GESIEVSCTA SGNPPPQIMW FKDNETLVED SGIVLKDGNR NLTIRRVRKE DEGLYTCQAC SVLGCAKVEA FFIIEGAQEK TNLEIIILVG TAVIAMFFWL LLVIILRTVK RANGGELKTG YLSIVMDPDE LPLDEHCERL PYDASKWEFP RDRLKLGKPL GRGAFGQVIE ADAFGIDKTA TCRTVAVKML KEGATHSEHR ALMSELKILI HIGHHLNVVN LLGACTKPGG PLMVIVEFCK FGNLSTYLRS KRNEFVPYKT KGARFRQGKD YVGAIPVDLK RRLDSITSSQ SSASSGFVEE KSLSDVEEEE APEDLYKDFL TLEHLICYSF QVAKGMEFLA SRKCIHRDLA ARNILLSEKN VVKICDFGLA RDIYKDPDYV RKGDARLPLK WMAPETIFDR VYTIQSDVWS FGVLLWEIFS LGASPYPGVK IDEEFCRRLK EGTRMRAPDY TTPEMYQTML DCWHGEPSQR PTFSELVEHL GNLLQANAQQ DGKDYIVLPI SETLSMEEDS GLSLPTSPVS CMEEEEVCDP KFHYDNTAGI SQYLQNSKRK SRPVSVKTFE DIPLEEPEVK VIPDDNQTDS GMVLASEELK TLEDRTKLSP SFGGMVPSKS RESVASEGSN QTSGYQSGYH SDDTDTTVYS SEEAELLKLI EIGVQTGSTA QILQPDSGTT LSSPPV