Biological process  Immune response
 Molecular function  Defense/immunity protein activity
 
Protein   alpha-1-microglobulin/bikunin precursor  Gene symbol   AMBP
 
 Cellular component  
     
 
Component
Cytoplasm
Endoplasmic reticulum
Extracellular
Golgi apparatus
Plasma membrane
 
   
 
Experimental evidence   
  Total number of studies : 35    
 
Peptide sequence Method Platform  Sample  Reference
Mass spectrometry LTQ-Orbitrap Plasma Schenk et al. 2008
Mass spectrometry Q-TOF Plasma Bastos-Amador et al. 2012
single radial immunodiffusion - Serum Takagi et al. 1980
Multiple reaction monitoring 4000 QTRAP Plasma Randall et al. 2010
Mass spectrometry Plasma Liu et al. 2007
Mass spectrometry LCQ Duo Serum Gundry et al. 2007
Mass spectrometry LTQ Orbitrap XL Plasma Bassani-Sternberg et al. 2010
Mass spectrometry 4800 Plus MALDI TOF/TOF Plasma Madian et al. 2010
Mass spectrometry LTQ Orbitrap XL Plasma Madian et al. 2010
Mass spectrometry LCQ Deca XP Plus Serum Adkins et al. 2003
Mass spectrometry Fourier transform ion cyclotron resonance (FT_ICR) Plasma Qian et al. 2010
Mass spectrometry LTQ Orbitrap XL Plasma Panchaud et al. 2009
Mass spectrometry LTQ Orbitrap XL Plasma Kang et al. 2010
ELISA - Plasma Mendez et al. 1986
Mass spectrometry Finnigan LTQ MS Plasma Fujii et al. 2005
Mass spectrometry Fourier transform ion cyclotron resonance (FT_ICR) Plasma Qian et al. 2005
Mass spectrometry LTQ linear ion trap Plasma Jin et al. 2005
Mass spectrometry MALDI-TOF/TOF Serum Misek et al. 2005
Mass spectrometry LTQ linear ion trap Serum He et al. 2005
Mass spectrometry LCQ Deca Plasma Moritz et al. 2005
Mass spectrometry LTQ linear ion trap Plasma Tu et al. 2005
Mass spectrometry - Plasma Michel et al. 2006
Mass spectrometry IMS-TOF Plasma Valentine et al. 2006
Mass spectrometry Q-TOF Plasma Kim et al. 2007
Mass spectrometry LTQ FT Serum Sennels et al. 2007
Mass spectrometry Agilent 1100 LC/MSD Trap XCT Plus System Plasma Ahrends et al. 2009
Mass spectrometry 4800 Plus MALDI TOF/TOF Plasma Jeong et al. 2010
Mass spectrometry LTQ FT Plasma Prentice et al. 2010
Mass spectrometry LTQ Plasma Tu et al. 2010
Mass spectrometry LTQ Orbitrap Plasma Shuford et al. 2010
Mass spectrometry MALDI-TOF/TOF Plasma Ignjatovic et al. 2011
Mass spectrometry - Plasma Farrah et al. 2011
Oucerlony immunodiffusion - Serum Ekstrom et al. 1977
Mass Spectrometry LTQ Plasma Kullolli et al. 2009
Mass spectrometry LCQ Deca XP Plus Plasma/Serum Yang et al. 2005
Mass spectrometry LCQ DECA XP Serum Yang et al. 2004
 
   
 
 Multiple reaction monitoring data  
     
 
Peptide sequence MH+ Sample Number of studies Reference
ETLLQDFR  1021.5  Plasma  Randall et al. 2010
 
   
 
  Protein concentration    
     
 
Protein concentration Method Sample
Reference
25  μg/ml Plasma Qian et al. 2005
25  μg/ml Plasma Tu et al. 2010
44  μg/ml Serum Gundry et al. 2007
48  μg/ml Spectral counting  Plasma Farrah et al. 2011
60  μg/ml Plasma Wu et al. 2003
25-83  μg/ml single radial immunodiffusion  Serum Takagi et al. 1980
 
   
 
  Extracellular vesicle proteins    
     
 
Sample Isolation  Experimental method Vesiclepedia accession Reference
Plasma  Differential centrifugation|Filtration|Ultracenrifugation|Sucrose density gradient  Mass spectrometry [Q-TOF]  Vesiclepedia_259 Bastos-Amador et al. 2012 
 
   
 
 Architecture  
     
 
Domains Motifs
KUNITZ   229 - 282
KUNITZ   285 - 338
SP   1 - 19
 
   
 
 External links  
     
 
HPRD UniProt NetPath 
01467  P02760  NetPath_M259 
 
   
 
 
 Protein sequence  NP_001624.1
     
   
    MRSLGALLLL LSACLAVSAG PVPTPPDNIQ VQENFNISRI YGKWYNLAIG STCPWLKKIM DRMTVSTLVL GEGATEAEIS MTSTRWRKGV CEETSGAYEK TDTDGKFLYH KSKWNITMES
YVVHTNYDEY AIFLTKKFSR HHGPTITAKL YGRAPQLRET LLQDFRVVAQ GVGIPEDSIF TMADRGECVP GEQEPEPILI PRVRRAVLPQ EEEGSGGGQL VTEVTKKEDS CQLGYSAGPC
MGMTSRYFYN GTSMACETFQ YGGCMGNGNN FVTEKECLQT CRTVAACNLP IVRGPCRAFI QLWAFDAVKG KCVLFPYGGC QGNGNKFYSE KECREYCGVP GDGDEELLRF SN