Biological process  Cell communication ; Signal transduction
 Molecular function  Defense/immunity protein activity
 
Protein   alpha-2-HS-glycoprotein  Gene symbol   AHSG
 
 Cellular component  
     
 
Component
Extracellular
 
   
 
Experimental evidence   
  Total number of studies : 50    
 
Peptide sequence Method Platform  Sample  Reference
ELISA - Serum Porazko et al. 2008
ELISA - serum Kirkpantur et al. 2009
ELISA - Serum Cagli et al. 2010
Mass spectrometry LTQ-Orbitrap Plasma Schenk et al. 2008
Mass spectrometry Q-TOF Plasma Bastos-Amador et al. 2012
Mass spectrometry LTQ Orbitrap Velos Plasma Kalra et al. 2013
Radial immunodiffusion - serum Voros et al. 2011
Single radial immunodiffusion - Serum Storiko et al. 1968
Multiple reaction monitoring 6490 QQQ Plasma Percy et al. 2013
Multiple reaction monitoring 6490 QQQ Blood Chambers et al. 2012
Multiple reaction monitoring TSQ Vantage Plasma Huttenhain et al. 2012
Multiple reaction monitoring 4000 QTRAP Plasma Randall et al. 2010
Mass spectrometry LCQ DecaXP Serum Tirumalai et al. 2003
Mass spectrometry Plasma Liu et al. 2007
Mass spectrometry LCQ Duo Serum Gundry et al. 2007
Mass spectrometry LTQ FT Plasma Jia et al. 2009
Mass spectrometry LTQ Plasma Carrascal et al. 2009
Mass spectrometry QSTAR Pulsar Serum Zhou et al. 2004
Mass spectrometry LTQ FT Serum Zheng et al. 2006
Mass spectrometry Fourier transform ion cyclotron resonance (FT_ICR) Plasma Qian et al. 2010
Mass spectrometry LTQ Orbitrap XL Plasma Panchaud et al. 2009
Mass spectrometry 6340 Ion Trap LC/MS Plasma Zhang et al. 2008
Mass spectrometry LTQ Orbitrap XL Plasma Kang et al. 2010
2-D DIGE - Plasma Corzett et al. 2010
Mass spectrometry MALDI-TOF Plasma Chen et al. 2004
Mass spectrometry Finnigan LTQ MS Plasma Fujii et al. 2005
Mass spectrometry Fourier transform ion cyclotron resonance (FT_ICR) Plasma Qian et al. 2005
Mass spectrometry LTQ linear ion trap Plasma Jin et al. 2005
Mass spectrometry LCQ Deca XP Serum Barnea et al. 2005
Mass spectrometry LTQ linear ion trap Serum He et al. 2005
Mass spectrometry LCQ Deca Plasma Moritz et al. 2005
Mass spectrometry LTQ linear ion trap Plasma Tu et al. 2005
Mass spectrometry - Plasma Michel et al. 2006
Mass spectrometry Finnigan LTQ MS Plasma Okano et al. 2006
Mass spectrometry IMS-TOF Plasma Valentine et al. 2006
Mass spectrometry MALDI-TOF Plasma Manabe et al. 2007
Mass spectrometry IMS-TOF Plasma Manabe et al. 2007
Mass spectrometry LTQ FT Serum Sennels et al. 2007
Mass spectrometry Finnigan LTQ MS Plasma Dayarathna et al. 2008
Mass spectrometry Agilent 1100 LC/MSD Trap XCT Plus System Plasma Ahrends et al. 2009
Mass spectrometry 4800 Plus MALDI TOF/TOF Plasma Jeong et al. 2010
Mass spectrometry MALDI-TOF Plasma Darde et al. 2010
Mass spectrometry LTQ FT Plasma Prentice et al. 2010
Mass spectrometry LTQ Plasma Tu et al. 2010
Mass spectrometry LTQ Orbitrap Plasma Shuford et al. 2010
Mass spectrometry MALDI-TOF/TOF Plasma Bortner et al. 2010
Mass spectrometry LTQ Orbitrap XL Serum Sinclair et al. 2011
Mass spectrometry - Plasma Farrah et al. 2011
Mass spectrometry LCQ Deca XP Plus Plasma/Serum Yang et al. 2005
Mass spectrometry LCQ DECA XP Serum Yang et al. 2004
 
   
 
 Multiple reaction monitoring data  
     
 
Peptide sequence MH+ Sample Number of studies Reference
APHGPGLIYR  1080.5  Blood  Chambers et al. 2012
HTFMGVVSLGSPSGEVSHPR  2081  Plasma  Huttenhain et al. 2012
HTLNQIDEVK  1196.6  Plasma  Randall et al. 2010
HTLNQIDEVK  1196.6  Blood  Chambers et al. 2012
APHGPGLIYR  1080.5  Plasma  Percy et al. 2013
HTLNQIDEVK  1196.6  Plasma  Percy et al. 2013
 
   
 
  Protein concentration    
     
 
Protein concentration Method Sample
Reference
72.32  μg/ml Multiple reaction monitoring  Blood Chambers et al. 2012
82  μg/ml Spectral counting  Plasma Farrah et al. 2011
600  μg/ml Plasma Wu et al. 2003
600  μg/ml Serum Gundry et al. 2007
610  μg/ml Plasma Polanski et al. 2007
625  μg/ml Plasma Qian et al. 2005
630  μg/ml Plasma Tu et al. 2010
0.829+/-0.100  g/L ELISA  serum Kirkpantur et al. 2009
14-440  μg/ml Plasma Stefan et al. 2008
352.6+/-55.3  μg/ml ELISA  Serum Cagli et al. 2010
400-850  μg/ml Single radial immunodiffusion  Serum Storiko et al. 1968
619+/-96  mg/L Radial immunodiffusion  serum Voros et al. 2011
630-1000  μg/ml ELISA  Serum Porazko et al. 2008
810.89+/-173.43  μg/ml Serum Aksoy et al. 2009
 
   
 
  Extracellular vesicle proteins    
     
 
Sample Isolation  Experimental method Vesiclepedia accession Reference
Plasma  Differential centrifugation|Filtration|Ultracenrifugation|Sucrose density gradient  Mass spectrometry [Q-TOF]  Vesiclepedia_197 Bastos-Amador et al. 2012 
 
   
 
 Architecture  
     
 
Domains Motifs
CYSTATIN   21 - 133
CYSTATIN   145 - 248
SP   1 - 18
 
   
 
 External links  
     
 
HPRD UniProt NetPath 
00727  P02765  NetPath_M197 
 
   
 
 
 Protein sequence  NP_001613.2
     
   
    MKSLVLLLCL AQLWGCHSAP HGPGLIYRQP NCDDPETEEA ALVAIDYINQ NLPWGYKHTL NQIDEVKVWP QQPSGELFEI EIDTLETTCH VLDPTPVARC SVRQLKEHAV EGDCDFQLLK
LDGKFSVVYA KCDSSPDSAE DVRKVCQDCP LLAPLNDTRV VHAAKAALAA FNAQNNGSNF QLEEISRAQL VPLPPSTYVE FTVSGTDCVA KEATEAAKCN LLAEKQYGFC KATLSEKLGG
AEVAVTCMVF QTQPVSSQPQ PEGANEAVPT PVVDPDAPPS PPLGAPGLPP AGSPPDSHVL LAAPPGHQLH RAHYDLRHTF MGVVSLGSPS GEVSHPRKTR TVVQPSVGAA AGPVVPPCPG
RIRHFKV