Biological process  Immune response
 Molecular function  Defense/immunity protein activity
 
Protein   orosomucoid 1  Gene symbol   ORM1
 
 Cellular component  
     
 
Component
Extracellular
 
   
 
Experimental evidence   
  Total number of studies : 37    
 
Peptide sequence Method Platform  Sample  Reference
Immunoassay - Plasma Haab et al. 2005
Immunoelectrophoresis - Serum Korczowska et al. 2011
Mass spectrometry LTQ-Orbitrap Plasma Schenk et al. 2008
Mass spectrometry Q-TOF Plasma Bastos-Amador et al. 2012
Multiple reaction monitoring - Plasma Percy et al. 2012
Multiple reaction monitoring - Plasma Percy et al. 2013
Single radial immunodiffusion - Serum Storiko et al. 1968
Multiple reaction monitoring 6490 QQQ Plasma Percy et al. 2013
Multiple reaction monitoring 6490 QQQ Plasma Domanski et al. 2012
Multiple reaction monitoring 4000 QTRAP Plasma Kuzyk et al. 2009
Multiple reaction monitoring TSQ Quantum Ultra Serum Ahn et al. 2011
Mass spectrometry Plasma Liu et al. 2007
Mass spectrometry LCQ Duo Serum Gundry et al. 2007
Mass spectrometry LCQ Deca XP Plus Serum Adkins et al. 2003
Mass spectrometry Fourier transform ion cyclotron resonance (FT_ICR) Plasma Qian et al. 2010
Mass spectrometry LTQ Orbitrap XL Plasma Panchaud et al. 2009
Mass spectrometry LTQ Orbitrap XL Plasma Yadav et al. 2011
Mass spectrometry 6340 Ion Trap LC/MS Plasma Zhang et al. 2008
Mass spectrometry LTQ Orbitrap XL Plasma Kang et al. 2010
Mass spectrometry Fourier transform ion cyclotron resonance (FT_ICR) Plasma Qian et al. 2005
Mass spectrometry LTQ linear ion trap Plasma Jin et al. 2005
Mass spectrometry MALDI-TOF Plasma Nedelkov et al. 2005
Mass spectrometry MALDI-TOF/TOF Serum Misek et al. 2005
Mass spectrometry LCQ Deca XP Serum Barnea et al. 2005
Mass spectrometry LTQ linear ion trap Serum He et al. 2005
Mass spectrometry LCQ Deca Plasma Moritz et al. 2005
Mass spectrometry LTQ linear ion trap Plasma Tu et al. 2005
Mass spectrometry IMS-TOF Plasma Valentine et al. 2006
Mass spectrometry LTQ FT Serum Sennels et al. 2007
Mass spectrometry 4800 Plus MALDI TOF/TOF Plasma Jeong et al. 2010
Mass spectrometry LTQ FT Plasma Prentice et al. 2010
Mass spectrometry LTQ Plasma Tu et al. 2010
Mass spectrometry LTQ Orbitrap Plasma Shuford et al. 2010
Mass spectrometry LTQ Plasma Nakshatri et al. 2010
Mass spectrometry LTQ Orbitrap XL Serum Sinclair et al. 2011
Mass spectrometry - Plasma Farrah et al. 2011
Mass spectrometry LCQ DECA XP Serum Yang et al. 2004
 
   
 
 Multiple reaction monitoring data  
     
 
Peptide sequence MH+ Sample Number of studies Reference
NWGLSVYADKPETTK  1707.8  Plasma  Kuzyk et al. 2009
NWGLSVYADKPETTK  1714.8  Plasma  Domanski et al. 2012
NWGLSVYADKPETTK  1708.8  Plasma  Domanski et al. 2012
NWGLSVYADKPETTK  1708.8  Plasma  Percy et al. 2013
TEDTIFLR  993.5  Serum  Ahn et al. 2011
TEDTIFLR  1000.5  Serum  Ahn et al. 2011
 
   
 
  Protein concentration    
     
 
Protein concentration Method Sample
Reference
4.54  μg/ml Multiple reaction monitoring  Plasma Percy et al. 2012
220  μg/ml Spectral counting  Plasma Farrah et al. 2011
350  ng/ml Multiple reaction monitoring  Plasma Domanski et al. 2012
383  ng/ml Multiple reaction monitoring  Plasma Percy et al. 2013
610  μg/ml Immunoassay  Plasma Haab et al. 2005
610  μg/ml Plasma Panchaud et al. 2009
690  μg/ml Plasma Anderson et al. 2004
690  μg/ml Plasma Polanski et al. 2007
690  μg/ml Plasma Gundry et al. 2007
700  μg/ml Plasma Wu et al. 2003
870  μg/ml Plasma Qian et al. 2005
270-1615  μg/ml Immunoelectrophoresis  Serum Korczowska et al. 2011
700-1100  μg/ml Single radial immunodiffusion  Serum Storiko et al. 1968
 
   
 
  Extracellular vesicle proteins    
     
 
Sample Isolation  Experimental method Vesiclepedia accession Reference
Plasma  Differential centrifugation|Filtration|Ultracenrifugation|Sucrose density gradient  Mass spectrometry [Q-TOF]  Vesiclepedia_5004 Bastos-Amador et al. 2012 
 
   
 
 Architecture  
     
 
Domains Motifs
SP   1 - 19
 
   
 
 External links  
     
 
HPRD UniProt NetPath 
00724  P02763  NetPath_M5004 
 
   
 
 
 Protein sequence  NP_000598.2
     
   
    MALSWVLTVL SLLPLLEAQI PLCANLVPVP ITNATLDRIT GKWFYIASAF RNEEYNKSVQ EIQATFFYFT PNKTEDTIFL REYQTRQDQC IYNTTYLNVQ RENGTISRYV GGQEHFAHLL
ILRDTKTYML AFDVNDEKNW GLSVYADKPE TTKEQLGEFY EALDCLRIPK SDVVYTDWKK DKCEPLEKQH EKERKQEEGE S