Biological process  Transport
 Molecular function  Transporter activity
 
Protein   apolipoprotein A-II  Gene symbol   APOA2
 
 Cellular component  
     
 
Component
Extracellular
 
   
 
Experimental evidence   
  Total number of studies : 48    
 
Peptide sequence Method Platform  Sample  Reference
Electroimmunoassay - Plasma Koren et al. 1982
ELISA - Plasma Stein et al. 1986
Immunoassay - Plasma Haab et al. 2005
Mass spectrometry LTQ-Orbitrap Plasma Schenk et al. 2008
Mass spectrometry LTQ Plasma Looze et al. 2008
Mass spectrometry Q-TOF Plasma Bastos-Amador et al. 2012
Multiple reaction monitoring - Plasma Percy et al. 2012
Multiple reaction monitoring 4000 QTRAP Serum Kay et al. 2007
Multiple reaction monitoring TSQ Vantage Plasma Huttenhain et al. 2012
Multiple reaction monitoring 6490 QQQ Blood Chambers et al. 2012
Multiple reaction monitoring 6490 QQQ Plasma Domanski et al. 2012
Multiple reaction monitoring 6490 QQQ Plasma Percy et al. 2012
Multiple reaction monitoring 4000 QTRAP Plasma Kuzyk et al. 2009
Mass spectrometry LCQ DecaXP Serum Tirumalai et al. 2003
Mass spectrometry Plasma Liu et al. 2007
Mass spectrometry LCQ Duo Serum Gundry et al. 2007
Mass spectrometry 4800 Plus MALDI TOF/TOF Plasma Madian et al. 2010
Mass spectrometry LTQ Plasma Carrascal et al. 2009
Mass spectrometry QSTAR Pulsar Serum Zhou et al. 2004
Mass spectrometry LTQ Orbitrap XL Plasma Madian et al. 2010
Mass spectrometry LCQ Deca XP Plus Serum Adkins et al. 2003
Mass spectrometry Fourier transform ion cyclotron resonance (FT_ICR) Plasma Qian et al. 2010
Mass spectrometry LTQ Orbitrap XL Plasma Panchaud et al. 2009
Mass spectrometry LTQ Orbitrap XL Plasma Yadav et al. 2011
Mass spectrometry 6340 Ion Trap LC/MS Plasma Zhang et al. 2008
Mass spectrometry LTQ Orbitrap XL Plasma Kang et al. 2010
Mass spectrometry Fourier transform ion cyclotron resonance (FT_ICR) Plasma Qian et al. 2005
Mass spectrometry LTQ linear ion trap Plasma Jin et al. 2005
Mass spectrometry MALDI-TOF Plasma Nedelkov et al. 2005
Mass spectrometry LCQ Deca XP Serum Barnea et al. 2005
Mass spectrometry LTQ linear ion trap Serum He et al. 2005
Mass spectrometry LCQ Deca Plasma Moritz et al. 2005
Mass spectrometry LTQ linear ion trap Plasma Tu et al. 2005
Mass spectrometry - Plasma Michel et al. 2006
Mass spectrometry IMS-TOF Plasma Manabe et al. 2007
Mass spectrometry LTQ FT Serum Sennels et al. 2007
Mass spectrometry Finnigan LTQ MS Plasma Dayarathna et al. 2008
Mass spectrometry SELDI-TOF Plasma Sihlbom et al. 2008
Mass spectrometry Agilent XCT plus Serum Stempfer et al. 2008
Mass spectrometry Agilent 1100 LC/MSD Trap XCT Plus System Plasma Ahrends et al. 2009
Mass spectrometry 4800 Plus MALDI TOF/TOF Plasma Jeong et al. 2010
Mass spectrometry SELDI-TOF Serum Xue et al. 2010
Mass spectrometry LTQ FT Plasma Prentice et al. 2010
Mass spectrometry LTQ Plasma Tu et al. 2010
Mass spectrometry LTQ Orbitrap Plasma Shuford et al. 2010
Mass spectrometry LTQ Orbitrap XL Serum Sinclair et al. 2011
Mass spectrometry - Plasma Farrah et al. 2011
Mass spectrometry LCQ Deca XP Plus Plasma/Serum Yang et al. 2005
Mass spectrometry LCQ DECA XP Serum Yang et al. 2004
 
   
 
 Multiple reaction monitoring data  
     
 
Peptide sequence MH+ Sample Number of studies Reference
SPELQAEAK  971.5  Plasma  Kuzyk et al. 2009
SPELQAEAK  978.5  Plasma  Domanski et al. 2012
SPELQAEAK  972.5  Plasma  Domanski et al. 2012
SPELQAEAK  972.5  Plasma  Percy et al. 2012
SPELQAEAK  972.4  Blood  Chambers et al. 2012
SPELQAEAK  972.4  Plasma  Domanski et al. 2012
EPCVESLVSQYFQTVTDYGK  2349.2  Serum  Kay et al. 2007
EQLTPLIK  941.5  Plasma  Huttenhain et al. 2012
 
   
 
  Protein concentration    
     
 
Protein concentration Method Sample
Reference
88.6  μg/ml Multiple reaction monitoring  Plasma Percy et al. 2012
116.82  μg/ml Multiple reaction monitoring  Blood Chambers et al. 2012
240  μg/ml Plasma Anderson et al. 2004
240  μg/ml Plasma Polanski et al. 2007
240  μg/ml Plasma Gundry et al. 2007
300  μg/ml Immunoassay  Plasma Haab et al. 2005
300  μg/ml Plasma Panchaud et al. 2009
300  μg/ml Plasma Tu et al. 2010
460  μg/ml Plasma Wu et al. 2003
460  μg/ml Plasma Qian et al. 2005
520  μg/ml ELISA  Plasma Stein et al. 1986
520  μg/ml Plasma Shuford et al. 2010
750  μg/ml Spectral counting  Plasma Farrah et al. 2011
45.3  μg/ml Multiple reaction monitoring  Plasma Percy et al. 2012
53  μg/ml Multiple reaction monitoring  Plasma Percy et al. 2012
59.846  μg/ml Multiple reaction monitoring  Plasma Domanski et al. 2012
67+/-11  mg/dl Electroimmunoassay  Plasma Koren et al. 1982
 
   
 
  Extracellular vesicle proteins    
     
 
Sample Isolation  Experimental method Vesiclepedia accession Reference
Plasma - Normal  Filtration|Size exclusion|Sucrose density gradient  Mass spectrometry [LTQ]|Western blotting|Immunoelectron Microscopy  Vesiclepedia_336 Bastos-Amador et al. 2012 
Plasma  Differential centrifugation|Filtration|Ultracenrifugation|Sucrose density gradient  Mass spectrometry [Q-TOF]  Vesiclepedia_336 Bastos-Amador et al. 2012 
 
   
 
 Architecture  
     
 
Domains Motifs
SP   1 - 16
 
   
 
 External links  
     
 
HPRD UniProt NetPath 
00129  P02652  NetPath_M336 
 
   
 
 
 Protein sequence  NP_001634.1
     
   
    MKLLAATVLL LTICSLEGAL VRRQAKEPCV ESLVSQYFQT VTDYGKDLME KVKSPELQAE AKSYFEKSKE QLTPLIKKAG TELVNFLSYF VELGTQPATQ