Biological process  Cell growth and/or maintenance
 Molecular function  Structural molecule activity
 
Protein   afamin  Gene symbol   AFM
 
 Cellular component  
     
 
Component
Extracellular
 
   
 
Experimental evidence   
  Total number of studies : 39    
 
Peptide sequence Method Platform  Sample  Reference
ELISA - Plasma Jerkovic et al. 2005
ELISA - Plasma Dieplinger et al. 2009
Mass spectrometry LTQ-Orbitrap Plasma Schenk et al. 2008
Mass spectrometry Q-TOF Plasma Bastos-Amador et al. 2012
Multiple reaction monitoring - Plasma Percy et al. 2012
Multiple reaction monitoring 6490 QQQ Plasma Percy et al. 2013
Multiple reaction monitoring 6490 QQQ Blood Chambers et al. 2012
Multiple reaction monitoring 4000 QTRAP Plasma Kuzyk et al. 2009
Mass spectrometry Plasma Liu et al. 2007
Mass spectrometry LCQ Duo Serum Gundry et al. 2007
Mass spectrometry LTQ FT Plasma Jia et al. 2009
Mass spectrometry API QSTAR Pulsar i Plasma Wasinger et al. 2005
Mass spectrometry LCQ Deca XP Plus Serum Adkins et al. 2003
Mass spectrometry LTQ Orbitrap XL Plasma Panchaud et al. 2009
Mass spectrometry Fourier transform ion cyclotron resonance (FT_ICR) Plasma Qian et al. 2010
Mass spectrometry 6340 Ion Trap LC/MS Plasma Zhang et al. 2008
Mass spectrometry LTQ Orbitrap XL Plasma Kang et al. 2010
Mass spectrometry Fourier transform ion cyclotron resonance (FT_ICR) Plasma Qian et al. 2005
Mass spectrometry MALDI-TOF/TOF Serum Misek et al. 2005
Mass spectrometry LCQ Deca XP Serum Barnea et al. 2005
Mass spectrometry LTQ linear ion trap Serum He et al. 2005
Mass spectrometry LCQ Deca Plasma Moritz et al. 2005
Mass spectrometry LTQ linear ion trap Plasma Tu et al. 2005
Mass spectrometry - Plasma Michel et al. 2006
Mass spectrometry IMS-TOF Plasma Valentine et al. 2006
Mass spectrometry LTQ FT Serum Sennels et al. 2007
Mass spectrometry Agilent 1100 LC/MSD Trap XCT Plus System Plasma Ahrends et al. 2009
Mass spectrometry 4800 Plus MALDI TOF/TOF Plasma Kolla et al. 2009
Mass spectrometry 4800 Plus MALDI TOF/TOF Plasma Jeong et al. 2010
Mass spectrometry LTQ FT Plasma Prentice et al. 2010
Mass spectrometry LTQ Plasma Tu et al. 2010
Mass spectrometry MALDI-TOF Plasma Kolialexi et al. 2010
Mass spectrometry MALDI-TOF Plasma Fitzgerald et al. 2010
Mass spectrometry LTQ Orbitrap Plasma Shuford et al. 2010
Mass spectrometry MALDI-TOF/TOF Plasma Bortner et al. 2010
Mass spectrometry LTQ Orbitrap XL Serum Sinclair et al. 2011
Mass spectrometry - Plasma Farrah et al. 2011
Mass Spectrometry LTQ Plasma Kullolli et al. 2009
Mass spectrometry LCQ Deca XP Plus Plasma/Serum Yang et al. 2005
 
   
 
 Multiple reaction monitoring data  
     
 
Peptide sequence MH+ Sample Number of studies Reference
DADPDTFFAK  1125.5  Plasma  Kuzyk et al. 2009
DADPDTFFAK  1126.5  Blood  Chambers et al. 2012
IAPQLSTEELVSLGEK  1713.9  Plasma  Percy et al. 2013
LPNNVLQEK  1054.5  Plasma  Percy et al. 2013
DADPDTFFAK  1126.5  Plasma  Percy et al. 2013
 
   
 
  Protein concentration    
     
 
Protein concentration Method Sample
Reference
5.72  μg/ml Multiple reaction monitoring  Blood Chambers et al. 2012
30  μg/ml Serum Lichenstein et al. 1994
30  μg/ml Serum Gundry et al. 2007
35  μg/ml Multiple reaction monitoring  Plasma Percy et al. 2012
320  μg/ml Spectral counting  Plasma Farrah et al. 2011
34.6-116.1  μg/ml ELISA  Plasma Dieplinger et al. 2009
59.79?+/-?13.30  μg/ml ELISA  Plasma Jerkovic et al. 2005
 
   
 
  Extracellular vesicle proteins    
     
 
Sample Isolation  Experimental method Vesiclepedia accession Reference
Plasma  Differential centrifugation|Filtration|Ultracenrifugation|Sucrose density gradient  Mass spectrometry [Q-TOF]  Vesiclepedia_173 Bastos-Amador et al. 2012 
 
   
 
 Architecture  
     
 
Domains Motifs
Albumin   22 - 205
Albumin   212 - 397
Albumin   404 - 593
SP   1 - 21
 
   
 
 External links  
     
 
HPRD UniProt NetPath 
00073  P43652  NetPath_M173 
 
   
 
 
 Protein sequence  NP_001124.1
     
   
    MKLLKLTGFI FFLFFLTESL TLPTQPRDIE NFNSTQKFIE DNIEYITIIA FAQYVQEATF EEMEKLVKDM VEYKDRCMAD KTLPECSKLP NNVLQEKICA MEGLPQKHNF SHCCSKVDAQ
RRLCFFYNKK SDVGFLPPFP TLDPEEKCQA YESNRESLLN HFLYEVARRN PFVFAPTLLT VAVHFEEVAK SCCEEQNKVN CLQTRAIPVT QYLKAFSSYQ KHVCGALLKF GTKVVHFIYI
AILSQKFPKI EFKELISLVE DVSSNYDGCC EGDVVQCIRD TSKVMNHICS KQDSISSKIK ECCEKKIPER GQCIINSNKD DRPKDLSLRE GKFTDSENVC QERDADPDTF FAKFTFEYSR
RHPDLSIPEL LRIVQIYKDL LRNCCNTENP PGCYRYAEDK FNETTEKSLK MVQQECKHFQ NLGKDGLKYH YLIRLTKIAP QLSTEELVSL GEKMVTAFTT CCTLSEEFAC VDNLADLVFG
ELCGVNENRT INPAVDHCCK TNFAFRRPCF ESLKADKTYV PPPFSQDLFT FHADMCQSQN EELQRKTDRF LVNLVKLKHE LTDEELQSLF TNFANVVDKC CKAESPEVCF NEESPKIGN