Biological process  Transport
 Molecular function  Transporter activity
 
Protein   albumin  Gene symbol   ALB
 
 Cellular component  
     
 
Component
Extracellular
 
   
 
Experimental evidence   
  Total number of studies : 53    
 
Peptide sequence Method Platform  Sample  Reference
Immunoassay - Plasma Haab et al. 2005
Mass spectrometry LTQ Plasma Looze et al. 2008
Mass spectrometry Q-TOF Plasma Bastos-Amador et al. 2012
Mass spectrometry LTQ Orbitrap Velos Plasma Kalra et al. 2013
Multiple reaction monitoring - Plasma Percy et al. 2012
Single radial immunodiffusion - Serum Storiko et al. 1968
Multiple reaction monitoring 6490 QQQ Plasma Percy et al. 2013
Multiple reaction monitoring 6490 QQQ Blood Chambers et al. 2012
Multiple reaction monitoring 6490 QQQ Plasma Domanski et al. 2012
Multiple reaction monitoring 6490 QQQ Plasma Percy et al. 2012
Multiple reaction monitoring 4000 QTRAP Plasma Barton et al. 2009
Multiple reaction monitoring 4000 QTRAP Plasma Kuzyk et al. 2009
Multiple reaction monitoring 4000 QTRAP Plasma Anderson et al. 2009
Multiple reaction monitoring 4000 QTRAP Serum Kay et al. 2007
Multiple reaction monitoring TSQ Vantage Plasma Huttenhain et al. 2012
Mass spectrometry Plasma Liu et al. 2007
Mass spectrometry HCTultra Plasma Nissum et al. 2007
Mass spectrometry LTQ Orbitrap XL Plasma Bassani-Sternberg et al. 2010
Mass spectrometry 4800 Plus MALDI TOF/TOF Plasma Madian et al. 2010
Mass spectrometry LTQ Plasma Carrascal et al. 2009
Mass spectrometry QSTAR Pulsar Serum Zhou et al. 2004
Mass spectrometry LCQ Deca XP Plus Serum Adkins et al. 2003
Mass spectrometry Plasma Zhang et al. 2010
Mass spectrometry LTQ Orbitrap XL Plasma Panchaud et al. 2009
Mass spectrometry Fourier transform ion cyclotron resonance (FT_ICR) Plasma Qian et al. 2010
2-DE Plasma Bandow et al. 2010
Mass spectrometry 6340 Ion Trap LC/MS Plasma Zhang et al. 2008
2-D DIGE - Plasma Corzett et al. 2010
Mass spectrometry Fourier transform ion cyclotron resonance (FT_ICR) Plasma Qian et al. 2005
Mass spectrometry LTQ linear ion trap Plasma Jin et al. 2005
Mass spectrometry MALDI-TOF/TOF Serum Misek et al. 2005
Mass spectrometry LCQ Deca XP Serum Barnea et al. 2005
Mass spectrometry LTQ linear ion trap Serum He et al. 2005
Mass spectrometry LCQ Deca Plasma Moritz et al. 2005
Mass spectrometry LTQ linear ion trap Plasma Tu et al. 2005
Mass spectrometry - Plasma Michel et al. 2006
Mass spectrometry IMS-TOF Plasma Valentine et al. 2006
Mass spectrometry MALDI-TOF Plasma Manabe et al. 2007
Mass spectrometry LTQ linear ion trap Serum Yu et al. 2007
Mass spectrometry IMS-TOF Plasma Manabe et al. 2007
Mass spectrometry LTQ FT Serum Sennels et al. 2007
Mass spectrometry SELDI-TOF Plasma Sihlbom et al. 2008
Mass spectrometry Agilent XCT plus Serum Stempfer et al. 2008
Mass spectrometry LTQ-Orbitrap Plasma Greening et al. 2009
Mass spectrometry Agilent 1100 LC/MSD Trap XCT Plus System Plasma Ahrends et al. 2009
Mass spectrometry 4800 Plus MALDI TOF/TOF Plasma Kolla et al. 2009
Mass spectrometry 4800 Plus MALDI TOF/TOF Plasma Jeong et al. 2010
Mass spectrometry LTQ Plasma Tu et al. 2010
Mass spectrometry LTQ Orbitrap Plasma Shuford et al. 2010
Mass spectrometry LTQ Plasma Nakshatri et al. 2010
Mass spectrometry LTQ Orbitrap XL Serum Sinclair et al. 2011
Mass spectrometry - Plasma Farrah et al. 2011
Mass spectrometry LCQ DECA XP Serum Yang et al. 2004
 
   
 
 Multiple reaction monitoring data  
     
 
Peptide sequence MH+ Sample Number of studies Reference
LVNEVTEFAK  1155.6  Plasma  Domanski et al. 2012
LVNEVTEFAK  1148  Plasma  Domanski et al. 2012
LVNEVTEFAK  1149.6  Blood  Chambers et al. 2012
LVNEVTEFAK  1148.8  Serum  Kay et al. 2007
LVNEVTEFAK  1148.6  Plasma  Kuzyk et al. 2009
VFDEFKPLVEEPQNLIK  2045.1  Plasma  Huttenhain et al. 2012
LVNEVTEFAK  1149.6  Plasma  Percy et al. 2012
LVNEVTEFAK  1149.6  Plasma  Barton et al. 2009
LVNEVTEFAK  1149.6  Plasma  Anderson et al. 2009
LVNEVTEFAK  1149.6  Plasma  Domanski et al. 2012
AEFAEVSK  880.4  Plasma  Percy et al. 2013
FQNALLVR  960.5  Plasma  Percy et al. 2013
SLHTLFGDK  1017.5  Plasma  Percy et al. 2013
 
   
 
  Protein concentration    
     
 
Protein concentration Method Sample
Reference
1.6  mg/ml Spectral counting  Plasma Farrah et al. 2011
33.3  mg/ml Multiple reaction monitoring  Plasma Percy et al. 2012
36.38  mg/ml Multiple reaction monitoring  Plasma Domanski et al. 2012
40  mg/ml Immunoassay  Plasma Haab et al. 2005
40  mg/ml Plasma Panchaud et al. 2009
40  mg/ml Plasma Tu et al. 2010
41  mg/ml Plasma Anderson et al. 2004
41  mg/ml Plasma Polanski et al. 2007
42  mg/ml Multiple reaction monitoring  Plasma Percy et al. 2012
45  mg/ml Plasma Wu et al. 2003
45  mg/ml Plasma Qian et al. 2005
35-50  mg/ml serum Adkins et al. 2003
35-50  mg/ml Plasma Shen et al. 2004
39-55  mg/ml Single radial immunodiffusion  Serum Storiko et al. 1968
76  mg/ml Multiple reaction monitoring  Blood Chambers et al. 2012
 
   
 
  Extracellular vesicle proteins    
     
 
Sample Isolation  Experimental method Vesiclepedia accession Reference
Plasma - Normal  Filtration|Size exclusion|Sucrose density gradient  Mass spectrometry [LTQ]|Western blotting|Immunoelectron Microscopy  Vesiclepedia_213 Bastos-Amador et al. 2012 
Plasma  Differential centrifugation|Filtration|Ultracenrifugation|Sucrose density gradient  Mass spectrometry [Q-TOF]  Vesiclepedia_213 Bastos-Amador et al. 2012 
 
   
 
 Architecture  
     
 
Domains Motifs
Albumin   415 - 609
Albumin   25 - 222
Albumin   223 - 414
SP   1 - 24
 
   
 
 External links  
     
 
HPRD UniProt NetPath 
00062  P02768  NetPath_M213 
 
   
 
 
 Protein sequence  NP_000468.1
     
   
    MKWVTFISLL FLFSSAYSRG VFRRDAHKSE VAHRFKDLGE ENFKALVLIA FAQYLQQCPF EDHVKLVNEV TEFAKTCVAD ESAENCDKSL HTLFGDKLCT VATLRETYGE MADCCAKQEP
ERNECFLQHK DDNPNLPRLV RPEVDVMCTA FHDNEETFLK KYLYEIARRH PYFYAPELLF FAKRYKAAFT ECCQAADKAA CLLPKLDELR DEGKASSAKQ RLKCASLQKF GERAFKAWAV
ARLSQRFPKA EFAEVSKLVT DLTKVHTECC HGDLLECADD RADLAKYICE NQDSISSKLK ECCEKPLLEK SHCIAEVEND EMPADLPSLA ADFVESKDVC KNYAEAKDVF LGMFLYEYAR
RHPDYSVVLL LRLAKTYETT LEKCCAAADP HECYAKVFDE FKPLVEEPQN LIKQNCELFE QLGEYKFQNA LLVRYTKKVP QVSTPTLVEV SRNLGKVGSK CCKHPEAKRM PCAEDYLSVV
LNQLCVLHEK TPVSDRVTKC CTESLVNRRP CFSALEVDET YVPKEFNAET FTFHADICTL SEKERQIKKQ TALVELVKHK PKATKEQLKA VMDDFAAFVE KCCKADDKET CFAEEGKKLV
AASQAALGL