Biological process  Cell growth and/or maintenance
 Molecular function  Cytoskeletal protein binding
 
Protein   actinin, alpha 1  Gene symbol   ACTN1
 
 Cellular component  
     
 
Component
Cytoplasm
Cytoskeleton
Cytosol
Mitochondrial membrane
Mitochondrion
Nucleus
 
   
 
Experimental evidence   
  Total number of studies : 10    
 
Peptide sequence Method Platform  Sample  Reference
Mass spectrometry LTQ-Orbitrap Plasma Schenk et al. 2008
Mass spectrometry LTQ Orbitrap Velos Plasma Kalra et al. 2013
Mass spectrometry Plasma Liu et al. 2007
Mass spectrometry LTQ Orbitrap XL Plasma Bassani-Sternberg et al. 2010
Mass spectrometry Fourier transform ion cyclotron resonance (FT_ICR) Plasma Qian et al. 2010
Mass spectrometry Fourier transform ion cyclotron resonance (FT_ICR) Plasma Qian et al. 2005
Mass spectrometry LTQ FT Serum Sennels et al. 2007
Mass spectrometry LTQ FT Plasma Prentice et al. 2010
Mass spectrometry LTQ Plasma Tu et al. 2010
Mass spectrometry - Plasma Farrah et al. 2011
 
   
 
 Multiple reaction monitoring data  
     
 
Peptide sequence MH+ Sample Number of studies Reference
Data not present
 
   
 
  Protein concentration    
     
 
Protein concentration Method Sample
Reference
120  ng/ml Spectral counting  Plasma Farrah et al. 2011
 
   
 
  Extracellular vesicle proteins    
     
 
Sample Isolation  Experimental method Vesiclepedia accession Reference
Data not present
 
   
 
 Architecture  
     
 
Domains Motifs
CH   33 - 133
CH   146 - 245
EF   750 - 778
EF   791 - 819
SPECTRIN   274 - 384
SPECTRIN   397 - 498
SPECTRIN   512 - 619
 
   
 
 External links  
     
 
HPRD UniProt NetPath 
00020  P12814  NetPath_M87 
 
   
 
 
 Protein sequence  NP_001093.1
     
   
    MDHYDSQQTN DYMQPEEDWD RDLLLDPAWE KQQRKTFTAW CNSHLRKAGT QIENIEEDFR DGLKLMLLLE VISGERLAKP ERGKMRVHKI SNVNKALDFI ASKGVKLVSI GAEEIVDGNV
KMTLGMIWTI ILRFAIQDIS VEETSAKEGL LLWCQRKTAP YKNVNIQNFH ISWKDGLGFC ALIHRHRPEL IDYGKLRKDD PLTNLNTAFD VAEKYLDIPK MLDAEDIVGT ARPDEKAIMT
YVSSFYHAFS GAQKAETAAN RICKVLAVNQ ENEQLMEDYE KLASDLLEWI RRTIPWLENR VPENTMHAMQ QKLEDFRDYR RLHKPPKVQE KCQLEINFNT LQTKLRLSNR PAFMPSEGRM
VSDINNAWGC LEQVEKGYEE WLLNEIRRLE RLDHLAEKFR QKASIHEAWT DGKEAMLRQK DYETATLSEI KALLKKHEAF ESDLAAHQDR VEQIAAIAQE LNELDYYDSP SVNARCQKIC
DQWDNLGALT QKRREALERT EKLLETIDQL YLEYAKRAAP FNNWMEGAME DLQDTFIVHT IEEIQGLTTA HEQFKATLPD ADKERLAILG IHNEVSKIVQ TYHVNMAGTN PYTTITPQEI
NGKWDHVRQL VPRRDQALTE EHARQQHNER LRKQFGAQAN VIGPWIQTKM EEIGRISIEM HGTLEDQLSH LRQYEKSIVN YKPKIDQLEG DHQLIQEALI FDNKHTNYTM EHIRVGWEQL
LTTIARTINE VENQILTRDA KGISQEQMNE FRASFNHFDR DHSGTLGPEE FKACLISLGY DIGNDPQGEA EFARIMSIVD PNRLGVVTFQ AFIDFMSRET ADTDTADQVM ASFKILAGDK
NYITMDELRR ELPPDQAEYC IARMAPYTGP DSVPGALDYM SFSTALYGES DL